{"ID":2921851,"CreatedAt":"2026-06-02T02:42:49.606572591Z","UpdatedAt":"2026-06-03T19:49:55.6428996Z","DeletedAt":null,"paper_url":"https://arxiv.org/abs/2606.01434","arxiv_id":"2606.01434","title":"DrugClaw and DrugAudit: A Primary-Source-Grounded Agent and Authority-Aware Benchmark for Drug-Information Question Answering","abstract":"Drug-information question answering is a high-stakes setting where hallucinated facts can mislead clinical decision-making and the provenance of each cited fact matters as much as the fact itself. We present DrugClaw, a multi-agent retrieval-augmented system that queries a registry of drug and pharmacovigilance skills via a reflection-driven state-machine workflow and returns answers grounded in primary regulatory or peer-reviewed records. We also contribute DrugAudit, a 3,772-item authority-aware benchmark with an evaluation panel that scores upstream-of-gold source match, token-level semantic snippet overlap, and citation faithfulness under a dual-judge LLM-as-judge protocol with inter-judge kappa = 0.88 (almost-perfect). Across DrugAudit plus drug-related subsets of MedQA (751) and PubMedQA (512), DrugClaw is top-1 on every column of the headline table: composite Evidence Index under both judges, judge-mediated answer correctness, primary-source rate (0.918, +10.1 pp over next-best), faithfulness (0.887, +5.9 pp), MedQA (0.920), and PubMedQA (0.693).","short_abstract":"Drug-information question answering is a high-stakes setting where hallucinated facts can mislead clinical decision-making and the provenance of each cited fact matters as much as the fact itself. We present DrugClaw, a multi-agent retrieval-augmented system that queries a registry of drug and pharmacovigilance skills...","url_abs":"https://arxiv.org/abs/2606.01434","url_pdf":"https://arxiv.org/pdf/2606.01434v1","authors":"[\"Qing Wang\",\"Bo Li\",\"Jialu Liang\",\"Daling Shi\",\"Bob Zhang\",\"Qianqian Song\"]","published":"2026-05-31T20:11:05Z","proceeding":"cs.CL","tasks":"[\"cs.CL\"]","methods":"[\"Large Language Model\"]","has_code":false}
