{"ID":2893332,"CreatedAt":"2026-06-01T04:54:23.091178241Z","UpdatedAt":"2026-06-01T04:54:23.091178241Z","DeletedAt":null,"paper_url":"https://arxiv.org/abs/2507.12774","arxiv_id":"2507.12774","title":"A Comprehensive Survey of Electronic Health Record Modeling: From Deep Learning Approaches to Large Language Models","abstract":"Artificial intelligence (AI) has demonstrated significant potential in transforming healthcare through the analysis and modeling of electronic health records (EHRs). However, the inherent heterogeneity, temporal irregularity, and domain-specific nature of EHR data present unique challenges that differ fundamentally from those in vision and natural language tasks. This survey offers a comprehensive overview of recent advancements at the intersection of deep learning, large language models (LLMs), and EHR modeling. We introduce a unified taxonomy that spans five key design dimensions: data-centric approaches, neural architecture design, learning-focused strategies, multimodal learning, and LLM-based modeling systems. Within each dimension, we review representative methods addressing data quality enhancement, structural and temporal representation, self-supervised learning, and integration with clinical knowledge. We further highlight emerging trends such as foundation models, LLM-driven clinical agents, and EHR-to-text translation for downstream reasoning. Finally, we discuss open challenges in benchmarking, explainability, clinical alignment, and generalization across diverse clinical settings. This survey aims to provide a structured roadmap for advancing AI-driven EHR modeling and clinical decision support. For a comprehensive list of EHR-related methods, kindly refer to https://survey-on-tabular-data.github.io/.","short_abstract":"Artificial intelligence (AI) has demonstrated significant potential in transforming healthcare through the analysis and modeling of electronic health records (EHRs). However, the inherent heterogeneity, temporal irregularity, and domain-specific nature of EHR data present unique challenges that differ fundamentally fro...","url_abs":"https://arxiv.org/abs/2507.12774","url_pdf":"https://arxiv.org/pdf/2507.12774v1","authors":"[\"Weijieying Ren\",\"Jingxi Zhu\",\"Zehao Liu\",\"Tianxiang Zhao\",\"Vasant Honavar\"]","published":"2025-07-17T04:31:55Z","proceeding":"cs.LG","tasks":"[\"cs.LG\",\"cs.AI\",\"cs.CL\"]","methods":"[\"Large Language Model\",\"Language Model\"]","has_code":false}