{"ID":2890574,"CreatedAt":"2026-06-01T04:54:23.091178241Z","UpdatedAt":"2026-06-01T04:54:23.091178241Z","DeletedAt":null,"paper_url":"https://arxiv.org/abs/2507.19404","arxiv_id":"2507.19404","title":"A multi-dynamic low-rank deep image prior (ML-DIP) for 3D real-time cardiovascular MRI","abstract":"Purpose: To develop a reconstruction framework for 3D real-time cine cardiovascular magnetic resonance (CMR) from highly undersampled data without requiring fully sampled training datasets. Methods: We developed a multi-dynamic low-rank deep image prior (ML-DIP) framework that models spatial image content and deformation fields using separate neural networks. These sub-networks are jointly trained per scan to reconstruct the dynamic image series directly from undersampled k-space data. ML-DIP was evaluated on (i) a 3D cine digital phantom with simulated premature ventricular contractions (PVCs), (ii) ten healthy subjects (including two scanned during both rest and exercise), and (iii) 12 patients with a history of PVCs. Phantom results were assessed using peak signal-to-noise ratio (PSNR) and structural similarity index measure (SSIM). In vivo performance was evaluated by comparing left-ventricular function quantification (against 2D real-time cine) and image quality (against 2D real-time cine and binning-based 5D-Cine). Results: In the phantom study, ML-DIP achieved PSNR \u003e 29 dB and SSIM \u003e 0.90 for scan times as short as two minutes, while recovering cardiac motion, respiratory motion, and PVC events. In healthy subjects, ML-DIP yielded functional measurements comparable to 2D cine and higher image quality than 5D-Cine, including during exercise with high heart rates and bulk motion. In PVC patients, ML-DIP preserved beat-to-beat variability and reconstructed irregular beats, whereas 5D-Cine showed motion artifacts and information loss due to binning. Conclusion: ML-DIP enables high-quality 3D real-time CMR with acceleration factors exceeding 1,000 by learning low-rank spatial and motion representations from undersampled data, without relying on external fully sampled training datasets.","short_abstract":"Purpose: To develop a reconstruction framework for 3D real-time cine cardiovascular magnetic resonance (CMR) from highly undersampled data without requiring fully sampled training datasets. Methods: We developed a multi-dynamic low-rank deep image prior (ML-DIP) framework that models spatial image content and deformati...","url_abs":"https://arxiv.org/abs/2507.19404","url_pdf":"https://arxiv.org/pdf/2507.19404v4","authors":"[\"Chong Chen\",\"Marc Vornehm\",\"Zhenyu Bu\",\"Preethi Chandrasekaran\",\"Muhammad A. Sultan\",\"Syed M. Arshad\",\"Yingmin Liu\",\"Yuchi Han\",\"Rizwan Ahmad\"]","published":"2025-07-25T16:10:01Z","proceeding":"eess.IV","tasks":"[\"eess.IV\"]","methods":"[]","has_code":false}