{"ID":2876961,"CreatedAt":"2026-06-01T04:54:23.091178241Z","UpdatedAt":"2026-06-01T04:54:23.091178241Z","DeletedAt":null,"paper_url":"https://arxiv.org/abs/2508.20363","arxiv_id":"2508.20363","title":"Tumorigenesis as a trauma response: the fragmentation of morphogenetic memory drives neoplastic dissociation","abstract":"The mitigation of stress is a key challenge for all biological systems. Conditions of unresolvable stress have been associated with a diverse array of pathologies, from cancer to post-traumatic stress disorder (PTSD). Here, I unify insights from evolutionary and developmental biology with trauma psychology to present a novel framework for tumorigenesis which synthesizes stress-perception, tissue dysfunction, and the hallmarks of neoplastic growth. This view carries therapeutic implications, suggesting a reintegrative approach that seeks to return cancer cells to the homeostatic control of the surrounding tissue.","short_abstract":"The mitigation of stress is a key challenge for all biological systems. Conditions of unresolvable stress have been associated with a diverse array of pathologies, from cancer to post-traumatic stress disorder (PTSD). Here, I unify insights from evolutionary and developmental biology with trauma psychology to present a...","url_abs":"https://arxiv.org/abs/2508.20363","url_pdf":"https://arxiv.org/pdf/2508.20363v1","authors":"[\"Jordan Strasser\"]","published":"2025-08-28T02:21:43Z","proceeding":"q-bio.CB","tasks":"[\"q-bio.CB\",\"q-bio.NC\",\"q-bio.PE\",\"q-bio.TO\"]","methods":"[\"Large Language Model\"]","has_code":false}