{"ID":2862886,"CreatedAt":"2026-06-01T04:54:23.091178241Z","UpdatedAt":"2026-06-01T04:54:23.091178241Z","DeletedAt":null,"paper_url":"https://arxiv.org/abs/2509.26440","arxiv_id":"2509.26440","title":"Transformer Classification of Breast Lesions: The BreastDCEDL_AMBL Benchmark Dataset and 0.92 AUC Baseline","abstract":"Breast magnetic resonance imaging is a critical tool for cancer detection and treatment planning, but its clinical utility is hindered by poor specificity, leading to high false-positive rates and unnecessary biopsies. This study introduces a transformer-based framework for automated classification of breast lesions in dynamic contrast-enhanced MRI, addressing the challenge of distinguishing benign from malignant findings. We implemented a SegFormer architecture that achieved an AUC of 0.92 for lesion-level classification, with 100% sensitivity and 67% specificity at the patient level - potentially eliminating one-third of unnecessary biopsies without missing malignancies. The model quantifies malignant pixel distribution via semantic segmentation, producing interpretable spatial predictions that support clinical decision-making. To establish reproducible benchmarks, we curated BreastDCEDL_AMBL by transforming The Cancer Imaging Archive's AMBL collection into a standardized deep learning dataset with 88 patients and 133 annotated lesions (89 benign, 44 malignant). This resource addresses a key infrastructure gap, as existing public datasets lack benign lesion annotations, limiting benign-malignant classification research. Training incorporated an expanded cohort of over 1,200 patients through integration with BreastDCEDL datasets, validating transfer learning approaches despite primary tumor-only annotations. Public release of the dataset, models, and evaluation protocols provides the first standardized benchmark for DCE-MRI lesion classification, enabling methodological advancement toward clinical deployment.","short_abstract":"Breast magnetic resonance imaging is a critical tool for cancer detection and treatment planning, but its clinical utility is hindered by poor specificity, leading to high false-positive rates and unnecessary biopsies. This study introduces a transformer-based framework for automated classification of breast lesions in...","url_abs":"https://arxiv.org/abs/2509.26440","url_pdf":"https://arxiv.org/pdf/2509.26440v2","authors":"[\"Naomi Fridman\",\"Anat Goldstein\"]","published":"2025-09-30T15:58:02Z","proceeding":"cs.AI","tasks":"[\"cs.AI\"]","methods":"[\"Transformer\"]","has_code":false}