{"ID":2852702,"CreatedAt":"2026-06-01T04:54:23.091178241Z","UpdatedAt":"2026-06-01T04:54:23.091178241Z","DeletedAt":null,"paper_url":"https://arxiv.org/abs/2510.17402","arxiv_id":"2510.17402","title":"Leveraging Group Relative Policy Optimization to Advance Large Language Models in Traditional Chinese Medicine","abstract":"Traditional Chinese Medicine (TCM) presents a rich and structurally unique knowledge system that challenges conventional applications of large language models (LLMs). Although previous TCM-specific LLMs have shown progress through supervised fine-tuning, they often face limitations in alignment, data quality, and evaluation consistency. In this study, we introduce Ladder-base, the first TCM-focused LLM trained with Group Relative Policy Optimization (GRPO), a reinforcement learning method that improves reasoning and factual consistency by optimizing response selection based on intra-group comparisons. Ladder-base is built upon the Qwen2.5-7B-Instruct foundation model and trained exclusively on the textual subset of the TCM-Ladder benchmark, using 80 percent of the data for training and the remaining 20 percent split evenly between validation and test sets. Through standardized evaluation, Ladder-base demonstrates superior performance across multiple reasoning metrics when compared to both state-of-the-art general-purpose LLMs such as GPT-4, Gemini 2.5, Claude 3, and Qwen3 and domain-specific TCM models including BenTsao, HuatuoGPT2, and Zhongjing. These findings suggest that GRPO provides an effective and efficient strategy for aligning LLMs with expert-level reasoning in traditional medical domains and supports the development of trustworthy and clinically grounded TCM artificial intelligence systems.","short_abstract":"Traditional Chinese Medicine (TCM) presents a rich and structurally unique knowledge system that challenges conventional applications of large language models (LLMs). Although previous TCM-specific LLMs have shown progress through supervised fine-tuning, they often face limitations in alignment, data quality, and evalu...","url_abs":"https://arxiv.org/abs/2510.17402","url_pdf":"https://arxiv.org/pdf/2510.17402v1","authors":"[\"Jiacheng Xie\",\"Shuai Zeng\",\"Yang Yu\",\"Xiaoting Tang\",\"Guanghui An\",\"Dong Xu\"]","published":"2025-10-20T10:43:33Z","proceeding":"cs.CL","tasks":"[\"cs.CL\",\"cs.AI\",\"cs.LG\"]","methods":"[\"Reinforcement Learning\",\"Large Language Model\",\"Language Model\"]","has_code":false}