{"ID":2848125,"CreatedAt":"2026-06-01T04:54:23.091178241Z","UpdatedAt":"2026-06-01T04:54:23.091178241Z","DeletedAt":null,"paper_url":"https://arxiv.org/abs/2510.26635","arxiv_id":"2510.26635","title":"SAMRI: Segment Any MRI","abstract":"Summary: SAMRI is an MRI-specialized adaptation of the Segment Anything Model achieving superior whole-body MRI segmentation, particularly for small and clinically critical structures, through box and point prompts for rapid annotation. Purpose: Existing SAM adaptations treat MRI as a generic modality, overlooking variable tissue contrast, intensity inhomogeneity, and clinically important small structures. We propose an MRI-specialized foundation model with strong whole-body segmentation and zero-shot generalization for direct use on any MRI annotation task. Methods: SAMRI fine-tunes only the mask decoder of SAM (ViT-B/16), keeping encoders frozen to preserve pretrained representations and eliminate redundant passes-reducing training time by 94%, trainable parameters by 96%, and FLOPs by ~99% versus full-model retraining. Training used 1.1 million 2D slice-mask pairs from 30 datasets spanning 47 targets, T1/T2/FLAIR/DWI contrasts, and whole-body anatomy, with focal-Dice loss and bounding-box (with optional point) prompts. Sizes were stratified by mask area (small: \u003c0.5%; medium: 0.5-3.5%; large: \u003e3.5%), and significance assessed by the Wilcoxon signed-rank test. Results: SAMRI with box+point prompts achieved mean DSC 0.87 +/- 0.11 across 47 targets, outperforming MedSAM (0.74 +/- 0.24) by 17.6% (p \u003c 0.05), with largest gains for small (+42.4%) and medium (+26.9%) structures. On six zero-shot datasets, SAMRI achieved mean DSC 0.85, outperforming baselines. Inference requires only ~4.5 GB VRAM through an interactive interface on standard hardware. Conclusion: Decoder-only fine-tuning on a large, MRI-specific corpus delivers superior whole-body segmentation with strong zero-shot generalization, particularly for small and clinically salient structures. Public code, pretrained models, and an interactive interface make SAMRI deployable for MRI segmentation research and clinical workflows.","short_abstract":"Summary: SAMRI is an MRI-specialized adaptation of the Segment Anything Model achieving superior whole-body MRI segmentation, particularly for small and clinically critical structures, through box and point prompts for rapid annotation. Purpose: Existing SAM adaptations treat MRI as a generic modality, overlooking vari...","url_abs":"https://arxiv.org/abs/2510.26635","url_pdf":"https://arxiv.org/pdf/2510.26635v3","authors":"[\"Zhao Wang\",\"Wei Dai\",\"Thuy Thanh Dao\",\"Steffen Bollmann\",\"Hongfu Sun\",\"Craig Engstrom\",\"Shekhar S. Chandra\"]","published":"2025-10-30T16:04:00Z","proceeding":"eess.IV","tasks":"[\"eess.IV\",\"cs.CV\"]","methods":"[]","has_code":false}